CEFPODOXIME 200 MG + OFLOXACIN 200 MG

DESCRIPTION

Cefotec-O Tablet is a combination of (Cefpodoxime 200 Mg + Ofloxacin 200 Mg). It is an antibiotic used for the treatment of typhoid fever and respiratory tract infections (infections that affect various organs involved in breathing). Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) works by killing the bacteria, thereby preventing the further spread of infection.

INDICATION

• Respiratory Tract Infection : Respiratory tract infections (RTIs) are infections that affect parts of the body involved in breathing, such as the sinuses, throat, airways, or lungs. Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) is used for the treatment of respiratory tract infections such as: 
  1. Pharyngitis and tonsillitis: Infections that cause swelling and soreness in the throat and tonsils. 
  2. Sinusitis: The swelling of the tissues of your sinuses (hollow spaces located behind your nose and cheekbones, between your eyes, and at the lower end of your forehead). 
  3. Bronchitis: The swelling and irritation of bronchial tubes that regulate air passage in the lungs. 
  4. Pneumonia: An infection in the air sacs of one or both lungs.

• Typhoid fever : Typhoid fever is an infection caused by Salmonella Typhi bacteria. The symptoms include high fever, diarrhoea, vomiting, etc. Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) is used for the treatment of typhoid fever.

MECHANISM OF ACTION 

Cefpodoxime 200 mg is a third-generation cephalosporin that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This action disrupts the cross-linking of peptidoglycan, a key component of the cell wall, weakening its structure. As a result, the bacterial cell wall becomes compromised, causing osmotic instability, lysis, and death of the bacteria. Cefpodoxime is bactericidal, effective against both Gram-positive bacteria (e.g., Streptococcus pneumoniae, Staphylococcus aureus) and Gram-negative bacteria (e.g., Escherichia coli, Klebsiella pneumoniae). Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) is used to treat respiratory, urinary tract, and skin infections.

Ofloxacin 200 mg is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication. It targets two key bacterial enzymes: DNA gyrase (in Gram-negative bacteria) and topoisomerase IV (in Gram-positive bacteria). By inhibiting these enzymes, Ofloxacin prevents DNA supercoiling and DNA strand separation, essential processes for bacterial replication. This disruption leads to DNA damage, halting replication and transcription, and ultimately causing bacterial cell death. Ofloxacin is bactericidal and effective against a broad range of Gram-positive bacteria (e.g., Staphylococcus aureus, Streptococcus pneumoniae) and Gram-negative bacteria (e.g., Escherichia coli, Pseudomonas aeruginosa). Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) is commonly used to treat urinary tract infections, respiratory infections, skin infections, and other bacterial infections.

SIDE EFFECTS CEFOTEC-O TABLET

Major & minor side effects for Cefotec-O Tablet

• Stomach pain
• Decreased appetite
• Joint pain
• Change in taste
• Diarrhoea
• Blurred vision
• Dizziness
• Headache
• Muscle pain

DRUG INTERACTION

Drug-Drug Interactions: Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) may have interaction with vitamin supplements (calcium/vitamin D), diuretic medication (furosemide), Pain killer (aspirin), and bronchodilators (albuterol).

Drug-Food Interactions: Avoid intake of milk and dairy products.

Drug-Disease Interactions: Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) may interact with tendonitis (inflammation in tendons), epilepsy, kidney, and liver problems.

PRECAUTIONS 

Taking before Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) include monitoring for potential allergic reactions and gastrointestinal side effects such as stomach irritation or bleeding. Patients with liver or kidney impairment should use this medication cautiously and under medical supervision. Domperidone may increase the risk of cardiac arrhythmias, particularly in those with pre-existing heart conditions. It’s important to inform the healthcare provider about all medications being taken to avoid drug interactions. Pregnant or breastfeeding women should consult their doctor before using Cefotec-O Tablet (Cefpodoxime 200 Mg + Ofloxacin 200 Mg) combination.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.