DESCRIPTION

Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg) is a combination medication utilized for the treatment of gentle to direct lower respiratory tract contaminations as well as diseases of the skin, blood, urinary tract, etc. caused by microscopic organisms. This medication ought to be utilized with caution in patients with kidney maladies due to the expanded hazard of extreme antagonistic impacts.

INDICATION

Lower Respiratory Tract Infection : Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg) is utilized in the treatment of lower respiratory tract contaminations such as pneumonia, bronchitis, etc. caused by Streptococcus pneumoniae, Haemophilus influenzae, etc.

Skin and Skin Structure Infection : Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg) is utilized in the treatment of uncomplicated diseases of the skin and skin structures caused by microbes. These contaminations may incorporate tainted wounds, folliculitis, abscesses, cellulitis, ulcers, etc.

Urinary tract infection : Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg) is utilized in the treatment of uncomplicated urinary tract diseases caused by microscopic organisms such as Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, etc.

Bacterial Septicemia : Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg)is utilized in the treatment of septicemia, which is an disease of the blood, caused by microscopic organisms such as Staphylococcus aureus, Haemophilus influenzae, Escherichia coli, etc.

Bone and joint infections : Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg) is utilized in the treatment of bone and joint contaminations such as septic joint pain, osteomyelitis, etc. caused by microscopic organisms such as Pseudomonas aeruginosa, Staphylococci and Streptococci species, etc.

MECHANISM OF ACTION 
 

Cefuroxime : Cefuroxime is a second-generation cephalosporin anti-microbial that works by repressing bacterial cell divider amalgamation. It ties to penicillin-binding proteins (PBPs) on the bacterial cell divider, which pieces the cross-linking of peptidoglycan layers. This disturbance debilitates the cell divider, driving to cell lysis and death.

Sulbactam : Sulbactam is a beta-lactamase inhibitor. Beta-lactamases are proteins created by certain microscopic organisms that can inactivate beta-lactam anti-microbials, counting cefuroxime, by breaking down their beta-lactam ring structure. Sulbactam restrains these proteins, subsequently ensuring cefuroxime from debasement and expanding its adequacy against beta-lactamase-producing microbes.

DRUG INTRACTION

Drug-Drug Interactions: Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg) can increase nephrotoxicity when combined with aminoglycosides or diuretics and enhance bleeding risks with anticoagulants. Monitor kidney function and adjust doses as needed.

Drug-Food Interactions: Minimal interactions; take with food to improve absorption and reduce stomach upset. Avoid alcohol to prevent increased side effects.

Drug-Disease Interactions: Use cautiously in patients with kidney issues due to the potential for increased nephrotoxicity, and monitor closely if combined with other nephrotoxic agents.

SIDE EFFECTS OF CEFU-SB INJECTION
Major & minor side effects for Cefu-SB Injection 

• Sickness and Vomiting
• Fatigue
• Chills
• Edema
• Diarrhea
• Headache
• Itching of vagina or genital area
• Chest pain
• Difficult or agonizing urination
• Shortness of breath
• Change in taste
• Abdominal pain

PRECAUTIONS

When regulating Cefu SB Inj. (Cefuroxime 1500 mg + Sulbactam 750 mg), screen for unfavorably susceptible responses in patients with a history of penicillin or cephalosporin sensitivities. Alter measurements for those with renal disability and closely screen renal work. Maintain a strategic distance from utilizing calcium-containing arrangements concurrently and be cautious with anticoagulants due to dying dangers. Observe for Clostridium difficile-associated loose bowels and screen for nearby responses at the infusion location. Utilize cautiously amid pregnancy and lactation, and counsel a healthcare supplier as required.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.