DESCRIPTION

Itrotec-100 Capsule containing Itraconazole, is a potent antifungal medication used to combat a range of fungal infections affecting diverse areas of the body, including the lungs, nails, mouth, and throat. It functions by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes essential for their integrity and function. By disrupting ergosterol production, Itraconazole effectively impedes fungal growth and propagation, thereby aiding in the treatment of conditions like aspergillosis in the lungs, onychomycosis in the nails, and oral or esophageal candidiasis in the mucosal surfaces. This medication is typically administered orally in capsule form and requires careful dosage adjustments based on the severity and type of infection.

USES OF ITROTEC-100 CAPSULE

• Blastomycosis : Blastomycosis is a fungal infection that can affect your lungs and also other parts of the body such as skin, bones, and joints. This condition is mostly asymptomatic (does not show symptoms) in the early stages, and when the infection becomes severe, it shows symptoms like night sweats, fever, cough, weight loss, chest pain, tiredness, etc. Itrotec-100 Capsule slows down the growth of this fungus and prevents it from spreading, thus it helps in treating the condition.

• Histoplasmosis : Histoplasmosis is a fungal infection that primarily affects your lungs. This condition may resolve on its own, but you will need treatment if the condition is severe. Itrotec-100 Capsule is used to treat this condition by preventing fungal growth.

• Invasive Aspergillosis : Invasive Aspergillosis is a fungal infection that mainly affects the lungs and spreads to other body parts like the brain, heart, kidney and skin. This infection may become life-threatening if you have a compromised immune system (immune system become weak due to certain medicines or diseases) or other underlying conditions. Itrotec-100 Capsule slows down the spread of this fungus and thus helps in treating the condition.

• Onychomycosis : Onychomycosis is a fungal infection in the fingernail and toenail. It is characterized by nail discolouration, ragged or crumbly nails, etc. Itrotec-100 Capsule helps prevent the spread of infection by reducing the growth of fungi.

• Vulvovaginal Candidiasis : Vulvovaginal candidiasis is a fungal infection in the vagina that causes itching and white discharge. . Itrotec-100 Capsule helps in treating its symptoms and reduces the growth of the fungus.

• Pityriasis versicolor : Pityriasis Versicolor is a fungal infection that affects the skin and leads to small flaky, discoloured patches on your chest and back. . Itrotec-100 Capsule works by killing fungus and preventing their growth. This relieves the different symptoms caused by the infection and speeds up the healing process.

•  Dermatophytoses : Dermatophytoses is the infection caused by a fungus that affects your skin, nails or scalp. Itrotec-100 Capsule stops the growth of fungus and helps in treating its symptoms like itchiness and rashes.

• Oral candidiasis : Oral candidiasis is a fungal infection that is seen in the mouth. This condition is characterised by white lesions on the tongue and inner cheeks. . Itrotec-100 Capsule reduces these white lesions by preventing the growth of fungus.

MECHANISM OF ACTION

Itraconazole 100 mg capsule exerts its antifungal activity by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. Ergosterol is crucial for maintaining the integrity and function of fungal cell membranes. By inhibiting the enzyme lanosterol 14α-demethylase, which is responsible for converting lanosterol to ergosterol, Itraconazole disrupts this process. As a result, fungal cell membranes become weakened and more permeable, leading to inhibition of fungal growth and replication.

PRECAUTION

Itraconazole requires careful monitoring due to potential impacts on health. It can affect liver function, causing elevated enzymes or severe damage, especially in patients with existing liver conditions. Serious cardiac effects, like heart failure, may occur in those with heart conditions, requiring cautious use and regular monitoring. It interacts with antibiotics, antivirals, and other medications, necessitating disclosure of all treatments to healthcare providers. Use during pregnancy and breastfeeding is generally discouraged due to fetal risks. Patients with impaired kidneys may need dosage adjustments to prevent elevated drug levels. Side effects include gastrointestinal issues and occasional neurological symptoms. Caution is urged for immunocompromised patients, who may need closer supervision. Limiting alcohol intake is crucial to avoid liver toxicity during treatment.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.