DESCRIPTION

Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg) is a combination pharmaceutical comprises of Ceftriaxone and Tazobactam. It is an anti-microbial utilized to treat bacterial contaminations influencing the lungs, nose, throat, skin, urinary tract, etc. It is moreover utilized to anticipate diseases at surgical destinations. This medication works by interferometer in the arrangement of the bacterial cell divider and inevitably murders them. Jacef TZ 1.125 Injection is not compelling against contaminations caused by infections.

INDICATION

• 
  Bacterial infections : Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg) is utilized for the treatment of diseases such as urinary tract diseases (an disease in any portion of your urinary framework (kidneys, bladder, ureters, or urethra), bone and joint contaminations (contaminations that can happen due to a bone/joint harm or through blood by which microscopic organisms, infection, or organisms attack a bone/joint), skin and skin structure contaminations (the contaminations that happen when the microscopic organisms attack the skin and its supporting structures), etc. caused by bacteria.

• Lower respiratory tract infection : Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg) is utilized to treat the taking after lung infections:
  1. Pneumonia is an disease of the discuss sacs in the lungs (either single or both lungs). It can be bacterial and viral. This tablet is utilized to treat pneumonia caused by bacteria.
  2. Bronchitis is the swelling and disturbance of bronchial tubes that controls discuss section in the lungs. It is utilized to treat bronchitis caused by bacteria.

• Intra-abdominal Infection : Intra-abdominal diseases (IAI) are stomach contaminations that incorporate peritonitis (swelling of the peritoneum-lining of the stomach divider), pancreatitis (swelling of the pancreas- an organ found behind the lower portion of the stomach), diverticulitis (swelling of diverticula- one or more little pockets in the digestive system), cholecystitis (swelling of the gallbladder-a little stomach related organ that sits fair beneath the liver), and cholangitis (swelling of the bile channel framework). Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg) is utilized to treat contaminations happening inside the midriff caused by bacteria.

• Surgical prophylaxis : Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg) is too utilized some time recently or after surgery to avoid bacterial diseases at surgical destinations.

MECHANISM OF ACTION

Ceftriaxone : Mechanism of Activity : Ceftriaxone is a cephalosporin anti-microbial that works by repressing bacterial cell divider union. It ties to penicillin-binding proteins (PBPs) on the bacterial cell divider, which hinders the cross-linking of peptidoglycan layers. This obstructions with cell divider union causes the bacterial cell to gotten to be unsteady and inevitably leads to cell lysis and death.

Tazobactam : Mechanism of Activity : Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are proteins delivered by a few microbes that can inactivate beta-lactam anti-microbials (like ceftriaxone) by breaking down their beta-lactam ring structure. Tazobactam restrains these proteins, ensuring ceftriaxone from being debased. This permits ceftriaxone to stay successful against microscopic organisms that would something else be safe due to the nearness of these chemicals.

DRUG INTERACTIONS

Drug-Drug Interaction : Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg) may associated with a blood more slender (heparin), drugs utilized to lower tall uric corrosive levels (probenecid), neuromuscular blocking specialist (vecuronium), anticancer medicate (methotrexate), water tablet (furosemide) and anti-microbials (chloramphenicol, gentamicin, streptomycin).

Drug-Food Interaction : No intuitive found.

Drug-Disease Interaction : If you have kidney or liver issues, the runs, hemolytic iron deficiency (lessening in ruddy blood cells that may cause breathlessness or shortcoming and make your skin pale yellow), kidney or irritate stones, aggravation of the huge digestive tract, educate your specialist some time recently taking Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg).

SIDE EFFECTS OF JACEF TZ 1.125  INJECTION
Major & minor side effects for Jacef TZ 1.125  Injection

• Nausea
• Vomiting
• Black or hesitate stools
• Chest pain
• Fever
• Difficulty or difficult urination
• Sore throat
• Diarrhoea
• Abdominal pain
• Dizziness
• Swelling of confront, lips, eyelids, tongue, hands and feet
• Acid or acrid stomach
• Change in taste
• Excessive discuss or gas in stomach

PRECAUTIONS

When utilizing Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg), key safeguards incorporate evaluating for penicillin or cephalosporin hypersensitivities due to potential cross-reactivity, observing renal and hepatic work since Jacef TZ 1.125 Inj. (Ceftriaxone 1000 mg + Tazobactam 125 mg). is fundamentally excreted by the kidneys and metabolized by the liver, dodging utilize with calcium-containing arrangements to avoid precipitation, and being cautious with anticoagulants due to an expanded chance of dying. Also, it is critical to screen for Clostridium difficile-associated the runs, consider the dangers and benefits of utilize amid pregnancy and lactation, and watch for nearby responses at the infusion location. Normal observing of renal and hepatic work is exhorted, particularly for patients with preexisting conditions or those on drawn out treatment.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.