N-ACETYLCYSTEINE 300 MG+PYRIDOXAMINE 50 MG

DESCRIPTION

Nephrotec-Forte (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg) Tablet  is used to manage chronic kidney disease (CKD), which involves a progressive loss of kidney function. In CKD, kidneys struggle to filter waste and excess fluid from the blood, leading to dangerous levels of toxins. This combination medication includes Acetylcysteine, an antioxidant that protects body tissues in individuals with CKD and those undergoing dialysis, and Pyridoxamine dihydrochloride, which helps metabolize fats, carbohydrates, and proteins, supporting energy balance. Together, they aid in improving kidney health and managing symptoms associated with chronic kidney disease.

INDICATION

• Chronic Kidney Disease (CKD) : Nephrotec-Forte Tablet (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg) Helps manage and slow the progression of kidney dysfunction by protecting kidney tissues and supporting metabolic processes.

 

• Antioxidant Support :  Nephrotec-Forte (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg) Tablet  acts as a potent antioxidant, helping to reduce oxidative stress and damage in kidney cells.

 

• Metabolism Regulation : Nephrotec-Forte  (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg) Tablet  aids in the metabolism of fats, carbohydrates, and proteins, which is crucial for maintaining energy levels in patients with kidney disease.

• Dialysis Support :  Nephrotec-Forte Tablet  (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg) Assists individuals undergoing dialysis by protecting against tissue damage and enhancing overall health.

• Detoxification :  Nephrotec-Forte Tablet (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg)  Helps in the removal of waste products from the body, alleviating the symptoms associated with the accumulation of toxins due to impaired kidney function.


 

MECHANISM OF ACTION

Acetylcysteine : Acetylcysteine (NAC) acts primarily as a potent antioxidant by increasing levels of glutathione, a key antioxidant in the body. This helps neutralize free radicals and reduce oxidative stress, which is particularly harmful in chronic kidney disease (CKD). By protecting kidney cells from oxidative damage, NAC supports overall renal health and function. Additionally, NAC plays a role in detoxification by promoting the removal of harmful substances, including toxins and metabolic waste, thereby alleviating the burden on the kidneys.

Pyridoxamine Dihydrochloride : Pyridoxamine dihydrochloride, a form of vitamin B6, facilitates the metabolism of essential nutrients such as fats, carbohydrates, and proteins. It serves as a coenzyme in various enzymatic reactions, supporting energy production and maintaining amino acid balance, which is crucial for overall health. Pyridoxamine also inhibits the formation of advanced glycation end products (AGEs), which are harmful compounds that can accumulate and contribute to kidney damage, particularly in diabetic patients.

DRUG INTERACTIONS

Drug-Drug Interactions : Nephrotec-Forte Tablet (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg) may interact with levodopa (reducing its effectiveness), isoniazid (altering tuberculosis treatment), and activated charcoal (decreasing Acetylcysteine's efficacy). It can also increase nephrotoxicity risks with aminoglycoside antibiotics and alter cardiovascular responses with glyceryl trinitrate.

Drug-Food Interactions : Patients are advised to limit the consumption of potassium and phosphate-rich foods to avoid complications, particularly for those with kidney concerns.

Drug-Disease Interactions : Caution is advised when using Nephrotec-Forte Tablet (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg)  in individuals with asthma (risk of exacerbation), stomach ulcers (potential gastrointestinal irritation), and liver disease (possible impact on drug metabolism). It should also be used carefully in those with serious skin rashes and allergies, as these conditions may increase the risk of adverse reactions.

SIDE EFFECT OF NEPHROTEC-AT TABLET
Major & Minor side effects for Nephrotec-Forte Tablet

• Nausea
• Vomiting
• Diarrhoea
• Abdominal pain

PRECAUTION

Before using Nephrotec-Forte Tablet (N-Acetylcysteine (NAC) 300 mg + Pyridoxamine 50 mg), patients should inform their healthcare provider of any existing respiratory conditions, gastrointestinal issues, or liver disease, as these may increase the risk of complications. Additionally, individuals with serious skin rashes or allergies should use this combination with caution due to the heightened potential for adverse reactions. Regular monitoring and consultation with a healthcare professional are essential for safe usage.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.