DESCRIPTION

Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR) is used to manage conditions involving excessive stomach acid and impaired gastrointestinal motility. Pantoprazole is a proton pump inhibitor that reduces stomach acid production, while Levosulpiride is a prokinetic agent that enhances gastric motility and alleviates symptoms like nausea and bloating. The sustained-release formulation of Levosulpiride provides prolonged symptom relief. Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR)  is effective for treating disorders like GERD with associated motility issues.

INDICATION

• Gastroesophageal Reflux Disease (GERD) :  Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR) is highly effective in managing GERD. Pantoprazole, a proton pump inhibitor, works by blocking the H+/K+ ATPase enzyme in the stomach lining, significantly reducing the production of stomach acid. This helps in alleviating symptoms like heartburn, acid reflux, and regurgitation by preventing acid from irritating the esophagus. Levosulpiride, a prokinetic agent, enhances gastric motility by antagonizing dopamine D2 receptors. This action speeds up gastric emptying and reduces the risk of reflux. Together, these medications provide comprehensive relief from GERD symptoms, promote healing of the esophageal lining, and improve overall digestive function.

Gastroesophageal Reflux Disease (GERD)

• Peptic Ulcers : Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR) treats peptic ulcers by reducing acid secretion with Pantoprazole and enhancing gastric motility with Levosulpiride. This dual action promotes ulcer healing, relieves pain, and prevents recurrence. Regular monitoring and adherence to prescribed dosages are crucial for effective ulcer management.

• Functional Dyspepsia : Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR) alleviates indigestion symptoms like bloating, nausea, and discomfort by improving gastric motility and reducing acid secretion. This combination enhances digestive function, providing relief and improving overall gastrointestinal comfort. Regular monitoring and adherence to prescribed dosages optimize management of functional dyspepsia.

Functional Dyspepsia

• Gastroparesis : Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR) enhances gastric motility, facilitating quicker stomach emptying to alleviate symptoms like early satiety and bloating. This combination improves digestive efficiency and reduces discomfort associated with delayed gastric emptying. Regular dosing and monitoring are essential for managing gastroparesis effectively.

• Irritable Bowel Syndrome (IBS) : Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR)helps alleviate gastrointestinal symptoms like abdominal pain and discomfort associated with IBS by improving digestive function. This combination supports smoother digestion, reduces bloating, and enhances overall gastrointestinal comfort. 

MECHANISM OF ACTION

Pantoprazole : Pantoprazole is a proton pump inhibitor (PPI) that works by irreversibly binding to the H+/K+ ATPase enzyme system in the gastric parietal cells. This inhibition blocks the final step of acid production, reducing both basal and stimulated gastric acid secretion. By lowering stomach acidity, Pantoprazole helps to heal and prevent peptic ulcers, manage gastroesophageal reflux disease (GERD), and alleviate symptoms like heartburn and regurgitation.

Levosulpiride (SR) : Levosulpiride, on the other hand, is a dopamine D2 receptor antagonist that acts primarily on the upper gastrointestinal tract. It enhances gastric motility by blocking dopamine receptors in the gut, thereby improving the coordination and strength of stomach contractions. This prokinetic action facilitates faster gastric emptying and reduces the retention of food and gastric contents, which can exacerbate symptoms such as bloating, early satiety, and nausea.

DRUG INTERACTIONS

Drug-Drug Interaction : Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR) may connected with drugs such as anti-fungal (ketoconazole, itraconazole, posaconazole) anti-cancer (erlotinib), blood more slender (warfarin, phenprocoumon), anti-HIV (atazanavir), a medicate utilized to treat rheumatoid joint pain, psoriasis, and cancer (methotrexate), anti-depressant (fluvoxamine), anti-microbial (rifampicin), and home grown supplement (St John’s wort).

Drug-Food Interaction :  smoking and liquor utilization. Liquor admissions leads to expanded generation of stomach corrosive, subsequently expanding sharpness and heartburn.

Drug-Disease Interaction : Advise your specialist if you have gastrointestinal dying, intestinal hindrance, pheochromocytoma (tumor of the adrenal organ), epilepsy, madness, Clostridium difficile-associated the runs (CDAD), liver infection, bone breaks, hypomagnesemia (moo levels of magnesium).

SIDE EFFECTS OF PANTOTEC-LS CAPSULE

Major & minor side effects for Pantotec-LS capsule 

• Nausea
• Vomiting
• Gas
• Dry mouth
• Dizziness
• Diarrhoea

PRECAUTION

Pantotec-LS Capsule (Pantoprazole 40 mg  + Levosulpiride 75 mg (SR)  combination necessitates careful consideration due to various factors: Levosulpiride may heighten cardiac arrhythmia risks, particularly in those with existing heart conditions, necessitating regular rhythm monitoring. Pantoprazole's potential gastrointestinal effects encompass nausea, diarrhea, or abdominal discomfort, necessitating prompt medical attention for severe symptoms. Patients with impaired kidney or liver function should receive cautious dosing adjustments. Both medications interact with other drugs, altering efficacy or inducing adverse reactions, underscoring the need for thorough medication disclosure. The use of Pantoprazole 40 mg + Levosulpiride 75 mg during pregnancy and lactation remains uncertain, necessitating use only under critical conditions and close medical supervision.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.