DESCRIPTION

Prab-NT Tablet (Pregabalin 75 mg + Nortriptyline 10 mg) is commonly prescribed for the management of neuropathic pain, which is pain resulting from nerve damage due to conditions like diabetes, shingles, or spinal cord injuries. Pregabalin, an anticonvulsant, works by stabilizing overactive nerve cells in the brain and spinal cord, thereby reducing the transmission of pain signals. Nortriptyline, a tricyclic antidepressant, enhances the effects by modulating neurotransmitters such as serotonin and norepinephrine, which play a role in mood and pain perception. Together, these medications provide a dual mechanism to not only alleviate pain but also improve sleep and overall quality of life for individuals suffering from chronic nerve pain. Additionally, Prab-NT Tablet (Pregabalin 75 mg + Nortriptyline 10 mg) may help reduce symptoms of anxiety and depression that often accompany chronic pain conditions.

INDICATION

• Neuropathic Torment : Prab-NT Tablet (Pregabalin 75 mg + Nortriptyline 10 mg) are both compelling in treating neuropathic torment, which may result from conditions like diabetic neuropathy or postherpetic neuralgia. Prab-NT Tablet diminishes nerve torment by tweaking neurotransmitter discharge, whereas Nortriptyline, atricyclic upper, gives extra torment help through its upper and pain relieving effects

• Chronic Torment Disorders :  Prab-NT Tablet (Pregabalin 75 mg + Nortriptyline 10 mg) can be utilized for unremitting torment conditions where neuropathic torment is a component, such as fibromyalgia.
   

• Depression-Related Pain : Prab-NT Tablet (Pregabalin 75 mg + Nortriptyline 10 mg) may help manage pain associated with depression. Prab-NT Tablet aims to enhance overall efficacy by targeting specific pain pathways, potentially improving the effectiveness of treatment for depression-related discomfort.

MECHANISM OF ACTION

Pregabalin : Calcium Channel Tweak: Pregabalin ties to the alpha-2-delta subunit of voltage-gated calcium channels in the central anxious framework. This authoritative decreases the convergence of calcium particles into neurons, which diminishes the discharge of excitatory neurotransmitters such as glutamate and substance P. This instrument makes a difference in lessening neuronal volatility and lightening neuropathic pain.

Nortriptyline : Norepinephrine and Serotonin Reuptake Inhibition: Nortriptyline is a tricyclic antidepressant that primarily functions by inhibiting the reuptake of norepinephrine and serotonin in the brain. This increases the levels of these neurotransmitters in the synaptic cleft, which can help improve mood and alleviate pain perception.

Pain Modulation: Nortriptyline also has analgesic properties, which enhance pain relief by affecting various pain pathways in the central nervous system. This contributes to its effectiveness in managing chronic pain disorders.

DRUG INTERACTIONS

Drug-Drug Intelligent : Prab-NT Tablet (Pregabalin 75 mg + Nortriptyline 10 mg) may connected with antidepressants (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline, citalopram, escitalopram, bupropion), torment executioner (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant (gabapentin, phenobarbital, phenytoin, clonazepam, topiramate), anti-anxiety (diazepam, alprazolam), sedative-hypnotics (zolpidem), antihistamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), antiemetic (ondansetron).

Drug-Food Intelligent : Dodge liquor utilization whereas taking Prab-NT Tablet as it might cause expanded laziness and sleepiness.

Drug-Disease Intuitive : Advise your specialist if you have angioedema, creatine kinase rises, heart issues, discouragement, fits, pheochromocytoma (tumor of the adrenal organ), bone marrow concealment, tardive dyskinesia (automatic facial developments), glaucoma, schizophrenia, bipolar clutter, thyroid issues, urinary maintenance, kidney and liver issues.

SIDE EFFECTS PRAB-NT TABLET 

Major & minor side effects for Prab-NT Tablet

• Chest tightness
• Swelling of confront, lips, eyelids, tongue
• Tiredness and weakness
• Blurred vision
• Dizziness
• Dry mouth
• Headache
• Loss of coordination
• Loss of bladder control
• Decreased intrigued in sexual intercourse
• Difficulty in urination
• Nausea
• Weight gain
• Swelling in the hands or feet
• Confusion
• Drowsiness

 

PRECAUTIONS

Prab-NT Tablet (Pregabalin 75 mg + Nortriptyline 10 mg) can cause laziness and discombobulation, so patients ought to be cautious with exercises requiring full sharpness. Pregabalin has potential for mishandle and ought to be utilized carefully in people with a history of substance mishandle. Nortriptyline can affect heart work and increment arrhythmia hazard, requiring cautious checking in those with cardiovascular conditions. Alter dosages for renal or hepatic impedance, and be cautious of serotonin disorder when combining with other serotonergic drugs. The security amid pregnancy and lactation is not well-established, and mental wellbeing ought to be observed due to the hazard of temperament changes and self-destructive contemplations.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.