DESCRIPTION

Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose), equating to 10 grams of Lactulose per 15 mL of solution. Lactulose is a synthetic disaccharide primarily used as a laxative to treat constipation and to manage hepatic encephalopathy in patients with liver disease. Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) works by drawing water into the bowel, softening stools and stimulating bowel movements. In hepatic encephalopathy, Lactulose helps reduce the absorption of ammonia in the gut, lowering blood ammonia levels and improving brain function. The concentrated form allows for precise dosing, making it suitable for both oral and rectal administration. Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) should be taken as directed to avoid side effects like bloating or diarrhea.

INDICATION

1. Chronic Constipation: Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) concentrate is an effective treatment for chronic constipation. Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) works by drawing water into the colon, softening stools, and increasing bowel movement frequency. Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) helps relieve the discomfort of hard, infrequent stools, making it easier to pass bowel movements.

2. Hepatic Encephalopathy: In patients with liver disease, Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) helps reduce elevated blood ammonia levels, a key cause of hepatic encephalopathy. By altering gut microbiota and trapping ammonia in the colon, Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) reduces ammonia absorption, thus preventing its toxic effects on the brain and improving cognitive function.

3. Laxative Use: Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) serves as a mild osmotic laxative, promoting regularity and easing the passage of stool over time. Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) is particularly useful for patients who need long-term relief from constipation without harsh side effects.

4. Bowel Cleansing: Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) is occasionally used to prepare patients for gastrointestinal procedures (such as colonoscopies). Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) helps clear the bowel by promoting stool evacuation, ensuring the colon is empty for better visualization during diagnostic exams.

MECHANISM OF ACTION

Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) works through its osmotic and metabolic effects. When ingested, Lactulose passes undigested into the colon, where it is fermented by gut bacteria into organic acids like lactic acid and acetic acid. This fermentation lowers the pH in the colon, which increases water retention in the stool, softening it and stimulating bowel movements, thus relieving constipation. In patients with hepatic encephalopathy, the acidic environment traps ammonia as ammonium ions (NH₄⁺), preventing its absorption into the bloodstream. This reduces blood ammonia levels, helping to alleviate symptoms of brain dysfunction associated with liver disease.
 

SIDE EFFECTS OF SOFTEC SOLUTION
Major & minor side effects for Softec Solution

• Diarrhoea
• Nausea or vomiting
• Stomach pain and cramps
• Belching
• Flatulence
• Low potassium and magnesium

DRUG INTERACTIONS

Drug-Drug Interactions : Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) may have interaction with diuretic (furosemide), laxatives (docusate, polyethylene glycol), anti-emetic (ondansetron), and anti-psychotic (quetiapine).

Drug-Food Interactions : No interactions found/established.

Drug-Disease Interactions : Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) may have interactions with conditions such as intestinal obstruction disorder, and galactosemia (galactose indigestion disorder).

PRECAUTIONS

When using Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose), it is important to exercise caution in patients with diabetes or those on a low-galactose diet, as Lactulose is a sugar that can affect blood glucose levels and may not be suitable for individuals with galactose intolerance. Softec Solution (Lactulose Concentrate is a solution that contains 66% w/v Lactulose) should be used with care in patients with a history of gastrointestinal disorders such as obstruction or irritable bowel syndrome (IBS). Overuse or excessive doses may lead to diarrhea, dehydration, or electrolyte imbalances. Regular monitoring is advised, particularly in patients with hepatic encephalopathy, to ensure the desired effects on ammonia levels without causing unwanted side effects. Pregnant and breastfeeding women should consult a healthcare provider before use.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.