DISCRIPTION

Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) is a medicine used to dissolve gallstones that are composed mainly of undissolved cholesterol. It is also used to improve the flow of bile in Primary Biliary Cirrhosis (a chronic condition in which the bile ducts in your liver are slowly damaged and destroyed). Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) works by breaking down the cholesterol in gallstones which helps in dissolving the stones. It improves the functioning of liver enzymes and protects liver cells.

INDICATION

• Primary Biliary Cholangitis (PBC) : Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) is a first-line treatment for Primary Biliary Cholangitis, a chronic autoimmune liver disease where the bile ducts in the liver become inflamed, leading to liver damage over time.

Primary Biliary Cholangitis (PBC)

• Gallstone Dissolution : Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) can be used to dissolve cholesterol gallstones in patients who are not suitable for surgical removal or as a preventive treatment post-gallbladder surgery (cholecystectomy).

Gallstone Dissolution

• Cholestasis of Pregnancy : Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) is sometimes used to manage cholestasis, a condition that occurs during pregnancy where bile flow from the liver is reduced, leading to itching and potential complications for both the mother and baby.

• Non-alcoholic Fatty Liver Disease (NAFLD) : Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) may be used in some cases to manage non-alcoholic fatty liver disease, especially when associated with elevated liver enzymes or inflammation.

Non-alcoholic Fatty Liver Disease (NAFLD)

• Primary Sclerosing Cholangitis (PSC) :Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) is sometimes used in the treatment of Primary Sclerosing Cholangitis, a chronic liver disease characterized by inflammation and scarring of the bile ducts.

MECHANISM OF ACTION 

Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) exhibits diverse therapeutic effects in liver and bile-related disorders. It reduces the cholesterol content of bile by decreasing hepatic cholesterol production and intestinal absorption, facilitating the dissolution of cholesterol gallstones. Additionally, UDCA protects hepatocytes from toxic bile acids, promoting the secretion of less harmful, hydrophilic bile acids that alleviate liver inflammation and damage. Its immunomodulatory properties are particularly beneficial in conditions such as primary biliary cholangitis (PBC), where UDCA helps regulate the immune response to prevent autoimmune attacks on bile ducts. Furthermore, UDCA enhances bile flow from the liver to the intestines, optimizing the clearance of bile acids and minimizing their hepatotoxic effects.

DRUG INTERACTIONS

Drug-Drug Interactions : Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) may have interaction with antibiotics (ciprofloxacin and dapsone), antihypertensive agents (nitrendipine), immunosuppressants (cyclosporine), hormone (oestrogen), antacids (aluminium hydroxide, aluminium carbonate, magaldrate).

Drug-Food Interactions : No interactions found/established.

Drug-Disease Interactions : Inform your doctor if you have biliary obstruction and liver impairment, variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), or liver encephalopathy.

SIDE EFFECTS URSOTEC-300 TABLET

Major & minor side effects for Ursotec-300 Tablet

• Diarrhoea
• Indigestion
• Bladder pain
• Nausea or Vomiting
• Unusual bleeding
• Weakness

PRECAUTIONS

Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg), typically prescribed in 300 mg tablets, requires careful consideration due to several precautions. It should be used cautiously during pregnancy and breastfeeding, with advice from a healthcare provider recommended. Patients with impaired liver function may require dosage adjustments or close monitoring. Before starting UDCA, individuals with acute cholecystitis or obstructive biliary tract disease should consult a healthcare provider. Ursotec-300 Tablet (Ursodeoxycholic acid 300 mg) can interact with medications like bile acid sequestrants, cyclosporine, and certain birth control pills, underscoring the importance of disclosing all medications to your healthcare provider. Common side effects include diarrhea, constipation, and abdominal discomfort; any severe or persistent side effects should be promptly reported. Always follow the dosage instructions provided by your healthcare provider or as indicated on the medication label.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice.. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.